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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6835 | Fenoldopam mesylate | Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 | Dopamine Receptor |
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. | |||
T2170 | SKF-96365 hydrochloride | SKF96365 | Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy |
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... | |||
T28790 | SKF1 | ||
SKF1 is a suppressor of the ability of FK506. SKF1 inhibits cell growth in the presence of high levels of NaCl, induces cell death in low salt conditions, interacts directly with yeast mitochodria. | |||
T25348 | Doxenitoin | LG-1,Glior,SKF2599,SKF 2599,SKF-2599 | |
Doxenitoin is an anticonvulsant agent. | |||
T1222 | Trifluoperazine dihydrochloride | Trifluoperazine 2HCl,SKF5019,Urinox | CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy |
Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. | |||
T34652 | SK&F 39728-A | SK&F39728-A,SK&F 1-39728,SK&F-39728-A,Skf 39728-A | |
SK&F 39728-A is a bioactive chemical. | |||
T2367 | SKF-86002 | SKF86002 | p38 MAPK , TNF |
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM). | |||
T28789 | SKF 89748 | SKF89748,SKF0-89748 | |
SKF 89748 is an agonists of alpha 1-adrenoceptor. | |||
T79914 | Tranylcypromine | SKF 385 | Monoamine Oxidase |
Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications. | |||
T81152 | SKF 81297 | Dopamine Receptor | |
SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1]. | |||
T26192 | SKF-107457 | SKF 107457,Ala-Ala-Phepsi(CH(OH)CH2)Gly-Val-Val-OCH3 | |
SKF-107457 is an HIV protease type 1 inhibitor. It is a hexapeptide substrate analog with the scissile bond being replaced by a hydroxy ethylene isostere. | |||
T60418 | Ropinirole | ||
Ropinirole (SKF 101468) is a selective D2-like family receptor agonist whereas it has no affinity for the D1 receptors. It is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor, which als... | |||
T60584 | Cimetidine hydrochloride | ||
Cimetidine (SKF-92334) hydrochloride is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride shows anti-cancer and anti-inflammatory activity. Cimetidine hydrochlori... | |||
T83662 | 2,3-dinor-8-iso Prostaglandin F1α | 2,3-dinor-8-iso PGF1α,2,3-dinor-iPF1α-III,2,3-dinor-5,6-dihydro-15-F2t-Isoprostane,2,3-dinor-5,6-dihydro-15-F2t-IsoP | |
2,3-Dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the... |